Protease Inhibitors and Phosphatase Inhibitors
.jpg-250.jpg)
MilliporeSigma™ Calbiochem™ Prostaglandin EP2 Receptor Antagonist, TG6-10-1
A cell-permeable, 3-acryl-acrylamide derivative that acts as a highly potent, selective, and competitive antagonist of prostaglandin E2 receptor (EP2, Kb =
MilliporeSigma™ Calbiochem™ β-Secretase Substrate IV, Fluorogenic
β-Secretase Substrate IV, Fluorogenic, is a highly sensitive FRET substrate. Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement.
MilliporeSigma™ Calbiochem™ USP1-UAF1 Inhibitor, ML323
A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC50 = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.
MilliporeSigma™ Calbiochem™ CBFβ-Runx1 Inhibitor II, Ro5-3335
A cell-permeable benzodiazepine that suppresses CBFα/Runx1-CBFβ transactivation activity (25μM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex
MilliporeSigma™ Calbiochem™ Arp2/3 Complex Inhibitor I, CK-666
The Arp2/3 Complex Inhibitor I, CK-666, also referenced under CAS 442633-00-3, controls the biological activity of Arp2/3. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Protease Arrest™ Reagent
An optimized concentration of various reversible and irreversible inhibitors to inhibit serine, cysteine, and calpain proteases.
MilliporeSigma™ Calbiochem™ Mevastatin, Sodium Salt
Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.
MilliporeSigma™ Calbiochem™ GSK-3β Inhibitor XI
The GSK-3β Inhibitor XI, also referenced under CAS 626604-39-5, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Deoxyhypusine Synthase Inhibitor, GC7
The Deoxyhypusine Synthase Inhibitor, GC7, also referenced under CAS 150333-69-0, controls the biological activity of Deoxyhypusine Synthase.
MilliporeSigma™ Calbiochem™ Olomoucine
A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases.
MilliporeSigma™ Calbiochem™ LRRK2 Inhibitor III, HG-10-102-01
A cell-permeable 2,4-diaminopyrimidinyl compound that acts as a potent, ATP-competitive LRRK2-selective inhibitor (IC5050 =
MilliporeSigma™ Calbiochem™ InSolution™ Wortmannin
Wortmannin is a fungal metabolite that acts as a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase).
MilliporeSigma™ Calbiochem™ Cdc25 Inhibitor IV, NSC 95397
The Cdc25 Inhibitor IV, NSC 95397, also referenced under CAS 93718-83-3, controls the biological activity of Cdc25. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ Cyclopamine-KAAD
A cell-permeable potent analog of Cyclopamine that specifically inhibits Hedgehog (Hh) signaling with similar or lower toxicity.
MilliporeSigma™ Calbiochem™ PARP Inhibitor I, 3-ABA
The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.