Protease Inhibitors and Phosphatase Inhibitors
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MilliporeSigma™ Calbiochem™ Ecotin, E. coli
A potent, broad range inhibitor of serine proteases.
MilliporeSigma™ Calbiochem™ PD 169316
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM).
MilliporeSigma™ Calbiochem™ CXCR4 Antagonist I, AMD3100
The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ PAD Inhibitor, Cl-amidine
Cl-amidine is a cell-permeable pan PAD inhibitor (IC50 = 0.8, 6.2, and 5.9 μM for PAD1, PAD3, and PAD4, respectively). Inactivates the calcium bound form of PAD4 in an irreversible manner.
MilliporeSigma™ Calbiochem™ LY 294002
LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC50 = 1.4 μM). Acts on the ATP-binding site.
MilliporeSigma™ Calbiochem™ InSolution™ LY 294002
InSolution™ LY 294002, CAS 154447-36-6, is a 10mm solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4μM).
MilliporeSigma™ Calbiochem™ Gemcitabine, HCl
A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties
MilliporeSigma™ Calbiochem™ Cyclophosphamide Monohydrate
A widely used anti-neoplastic agent that also displays immunosuppressant properties.
MilliporeSigma™ Calbiochem™ GGTI-2147
A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
MilliporeSigma™ Calbiochem™ Calmodulin Kinase IINtide
A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity).
MilliporeSigma™ Calbiochem™ InSolution™ Casein Kinase I Inhibitor, D4476
The InSolution™ Casein Kinase I Inhibitor, D4476 controls the biological activity of Casein Kinase I. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NS8593
An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels in a Ca2+-dependent manner.
MilliporeSigma™ Calbiochem™ α-Synuclein Blocker, ELN484228
A cell-permeable compound that reversibly binds to pocket I of the monomeric α-synuclein (α-syn) and reverses α-syn-induced impairment of phagocytosis in H4 neuroglioma cells.
MilliporeSigma™ Calbiochem™ PARP Inhibitor VIII, PJ34
The PARP Inhibitor VIII, PJ34, also referenced under CAS 344458-15-7, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Membrane Traffic Inhibitor, A5
The Membrane Traffic Inhibitor, A5 controls the biological activity of adaptor complex AP-1.